Functional Genomics of Parkinson's Disease
Members
| Coordinator | |
|---|---|
| Prof. Dr. Thomas Gasser Eberhard-Karls-University Tuebingen |
|
| Principal Investigator | Subproject |
| Prof. Dr. Thomas Gasser Eberhard-Karls-University Tuebingen |
|
| Prof. Dr. Christine Klein University of Luebeck Luebeck |
SP3: Mutations in recessive Parkinson's Disease genes |
|
PD Dr. Guenther Hoeglinger Philipps-University Marburg Marburg |
SP4: Genome-wide siRNA screen in alpha-synuclein-based in vitro models of Parkinson's Disease |
| Prof. Dr. Joerg Schulz University of Aachen Aachen |
SP5, 6a: Modifier Screen in flies overexpressing LRRK2 |
| Prof. Dr. Markus Zweckstetter University of Goettingen Goettingen |
SP6b: Molecular mechnisms of pathogenic misfolding of alpha-synuclein |
| Prof. Dr. Georg Auburger J. W. Goethe University Frankfurt |
SP7: Biomarkers of the common Parkinson pathway: alpha-synuclein induction and synaptic pathology in recessive PD |
| Prof. Dr. Olaf Riess Eberhard-Karls-University Tuebingen |
SP8: Calpain cleavage of alpha-synuclein int eh pathogenesis of Parkinson's Disease by cell culture and animal models |
| Prof. Dr. Philipp Kahle Eberhard-Karls-University Tuebingen |
SP9: Regulation of Apoptosis Signal Regulation Kinase Pathways by DJ-1 and Parkin |
| Prof Dr. Rejko Krüger Eberhard-Karls-University Tuebingen |
SP10: Mitochondrial stress response in neurodegeneration and aging: OMI and DJ-1 mediated signalling pathways |
| Prof. Dr. Christian Haass Ludwig-Maximilians-University Muenchen |
SP11: The physiological and pathological function of PINK 1, parkin and LRRK2 in zebrafish and other models |
|
Prof. Dr. Marius Ueffing Technical University Muenchen |
SP12: Functional characterization of LRRK2 in mammalian cells and tissue |
| Prof. Dr. Jochen Roeper J. W. Goethe University Frankfurt |
SP13a: Dopaminergic dysfunction and molecular pathways to selective neurodegeneration: from mouse models to Parkinson disease |
| Prof. Dr. Birgit Liss University of Ulm Ulm |
SP13b: Dopaminergic dysfunction and molecular pathways to selective neurodegeneration: from mouse models to Parkinson disease |
| Prof. Dr. Guntehr Schuetz German Cancer Research Center Heidelberg |
SP14a: Characterization of genetic mouse models for Parkinson's disease |
| Prof. Dr. Wolfgang Wurst Helmholtz Center Muenchen Neuherberg |
SP14b: Characterization of genetic mouse models for Parkinson's disease |
| Prof. Dr. Katrhin Marcus Ruhr University Bochum |
SP15: High-performance proteome analysis for biomarker discovery and elucidation of pathomechanisms |
| Prof Dr. Andreas Zell Eberhard-Karls-University Tuebingen |
SP16: Bioinformatics: data integration towards a systems level model of Parkinson's disease. Generation of a systems biology model |